Disease Markers / 2016 / Article / Tab 2 / Research Article
Association of the Aspartate Aminotransferase to Alanine Aminotransferase Ratio with BNP Level and Cardiovascular Mortality in the General Population: The Yamagata Study 10-Year Follow-Up Table 2 Univariate and multivariate logistic analyses to predict high BNP.
Variables Univariate analysis Multivariate analysis OR 95% CI OR 95% CI Age (years) 1.12 1.10–1.14 <0.0001 1.08 1.05–1.10 <0.0001 Men/women 0.71 0.51–0.98 0.0382 0.76 0.54–1.08 0.1300 BMI 0.97 0.92–1.02 0.2485 Previous CVD 5.94 4.22–8.36 <0.0001 3.53 2.46–5.07 <0.0001 Previous cancer 1.31 0.47–3.64 0.6049 Previous liver disease 0.56 0.14–2.31 0.4259 Smoking 1.32 0.94–1.85 0.1116 Alcohol consumption 1.09 0.77–1.52 0.6289 Hypertension 2.27 1.63–3.12 <0.0001 1.18 0.82–1.70 0.3697 Diabetes mellitus 1.82 1.08–3.08 0.0245 1.55 0.88–2.72 0.1258 Systolic BP 1.02 1.01–1.03 0.0016 Diastolic BP 1.00 0.99–1.02 0.6309 HbA1c 1.10 0.96–1.27 0.1785 FBS 1.03 0.84–1.18 0.6466 eGFR 0.47 0.37–0.57 <0.0001 0.71 0.58–0.86 0.0007 AST 1.04 0.97–1.12 0.2523 ALT 0.79 0.65–0.97 0.0234 1.04 0.66–1.18 0.3552 AST/ALT ratio 1.59 1.39–1.81 <0.0001 1.31 1.13–1.53 0.0004
ALT, alanine transaminase; AST, aspartate transaminase; BMI, body mass index; BNP, brain natriuretic peptide; BP, blood pressure; CVD, cardiovascular disease; eGFR, estimated glomerular filtration rate; FBS, fasting blood sugar;
