Biomarkers Discovery for Colorectal Cancer: A Review on Tumor Endothelial Markers as Perspective Candidates

Figure 1

Predicted molecular structure of the tumor endothelial markers (TEM1, TEM5, TEM7, and TEM8). EGF: epidermal growth factor-like domain; S: Sushi domain; C-LECT: C-lectin domain; GPS: proteolysis site; HormR: hormone receptor domain; RGD: Arg-Gly-Asp motif; Ig: immunoglobulin-like domain; LRRC: leucine-rich repeat C-terminal domain; LRR: leucine-rich repeat; PD: plexin-like domain; NIDO: nidogen-like domain; vWA: von Willebrand type A domain; aa: amino acids chain length.