Autoantibody Response to ZRF1 and KRR1 SEREX Antigens in Patients with Breast Tumors of Different Histological Types and Grades

Table 1

Characteristics of tumor patients and healthy donors.

Characteristics	Samples description
(1) Group of healthy donors
Number of healthy women	56
Age at diagnosis, years (range, mean ± SD)	17–60, 40,11 ± 12,20
The number of healthy donors 45 years old or older	21
The number of healthy donors younger than 45 years	35
(2) Group of patients with benign breast tumors
Number of fibroadenoma patients	22
Age at diagnosis, years (range, mean ± SD)	24–63, 30 ± 9,54
The number of fibroadenoma patients 45 years old or older	2
The number of fibroadenoma patients younger than 45 years	20
(3) Group of cancer patients
Number of patients	120
Age at diagnosis, years (range, mean ± SD)	36–83, ,63
The number of cancer patients 45 years old or older	112
The number of cancer patients younger than 45 years	8
Tumor type
Invasive ductal breast carcinoma	87
Invasive lobular breast carcinoma	23
Medullary breast cancer	10
Tumor grade (% from general)	83
	Grade 1: 4,82
	Grade 2: 37,35
	Grade 3: 57,83
ER-status (%)	52
Positive	71,1
Negative	28,9
PR-status (%)	52
Positive	30,8
Negative	69,2
HER-2/neu status (%)	52
Positive	30,8
Negative	69,2
Lymphoid nodes status (% of positive)	28,8

SD: standard deviation.