Detection of OSR2, VAV3, and PPFIA3 Methylation in the Serum of Patients with Gastric Cancer

Table 3

The positive rate of at least one hypermethylated gene in serum samples.

	OSR2 + VAV3 + PPFIA3 methylation		Positive percent	value
	Positive	Negative
GC	40	8	83.3%	<0.01
Normal	3	22	12%

When the markers were used in combination, the test was considered to be positive if one marker reached the threshold and negative if all three markers were negative.
Using chi-square for this statistic.
Statistically significant.