Research Article
Lymphocyte Antigen 75 Polymorphisms Are Associated with Disease Susceptibility and Phenotype in Japanese Patients with Inflammatory Bowel Disease
Table 2
Allele frequencies of SNPs in the LY75 gene in CD, UC, and healthy subjects.
| SNP number | dbSNP | Alleles (1>2) | Position (bp) | Gene location | CD () | UC () | Controls () | MAF (%) | HWE value | MAF (%) | HWE value | MAF (%) | HWE value |
| 1 | rs1511224 | G>A | 159894350 | Intron | 0.402 | 0.163 | 0.489 | 0.645 | 0.480 | 0.762 | 2 | rs16822581 | C>T | 159882166 | Exon | 0.431 | 0.221 | 0.335 | 0.619 | 0.329 | 0.893 | 3 | rs11690117 | C>A | 159841125 | Intron | 0.431 | 0.072 | 0.473 | 0.518 | 0.441 | 0.397 | 4 | rs13307 | C>T | 159803485 | Intron | 0.402 | 1.000 | 0.346 | 1.000 | 0.357 | 0.922 | 5 | rs1365798 | C>T | 159795853 | 3′ UTR | 0.186 | 0.254 | 0.282 | 1.000 | 0.307 | 0.704 |
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SNPs, single nucleotide polymorphisms; CD, Crohn’s disease; UC, ulcerative colitis; MAF, minor allele frequency; HWE, Hardy–Weinberg equilibrium.
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