Lymphocyte Antigen 75 Polymorphisms Are Associated with Disease Susceptibility and Phenotype in Japanese Patients with Inflammatory Bowel Disease

Table 2

Allele frequencies of SNPs in the LY75 gene in CD, UC, and healthy subjects.

SNP number	dbSNP	Alleles (1>2)	Position (bp)	Gene location	CD ()		UC ()		Controls ()
					MAF (%)	HWE value	MAF (%)	HWE value	MAF (%)	HWE value
1	rs1511224	G>A	159894350	Intron	0.402	0.163	0.489	0.645	0.480	0.762
2	rs16822581	C>T	159882166	Exon	0.431	0.221	0.335	0.619	0.329	0.893
3	rs11690117	C>A	159841125	Intron	0.431	0.072	0.473	0.518	0.441	0.397
4	rs13307	C>T	159803485	Intron	0.402	1.000	0.346	1.000	0.357	0.922
5	rs1365798	C>T	159795853	3′ UTR	0.186	0.254	0.282	1.000	0.307	0.704

SNPs, single nucleotide polymorphisms; CD, Crohn’s disease; UC, ulcerative colitis; MAF, minor allele frequency; HWE, Hardy–Weinberg equilibrium.