Circulating Omentin-1 Levels Are Decreased in Dilated Cardiomyopathy Patients with Overt Heart Failure
Table 1
Clinical characteristics of patients.
Characteristics
Control
DCM
DCM1
DCM2
DCM3
Age (years)
52 ± 12
54 ± 13
58 ± 11
54 ± 13
52 ± 15
Sex (male/female)
25/20
72/28
14/8
32/13
26/7
Smoking, (%)
10 (22.2)
24 (24.0)
2 (9.1)
13 (28.9)
9 (27.3)
BMI (Kg/m2)
25.6 ± 3.4
23.9 ± 3.8
23.4 ± 3.2
23.9 ± 3.2
24.3 ± 4.9
HR (bpm)
71 ± 10
90 ± 18
89 ± 19
87 ± 17
93 ± 19
SBP (mmHg)
122 ± 12
119 ± 15
124 ± 13
119 ± 14
116 ± 17
DBP (mmHg)
71 ± 9
76 ± 12
76 ± 9
75 ± 12
76 ± 15
TG (mmol/L)
1.57 ± 0.85
1.28 ± 0.73
1.09 ± 0.33
1.46 ± 0.95
1.16 ± 0.54
TC (mmol/L)
4.51 ± 0.98
4.19 ± 1.09
4.14 ± 1.31
4.31 ± 1.14
4.09 ± 0.86
HDL-C (mmol/L)
1.15 ± 0.29
1.06 ± 0.34
1.19 ± 0.40
1.08 ± 0.31
0.94 ± 0.30
LDL-C (mmol/L)
2.72 ± 0.80
2.70 ± 0.85
2.40 ± 0.70
2.83 ± 1.02
2.73 ± 0.62
GLU (mmol/L)
5.08 ± 0.54
4.95 ± 1.23
5.15 ± 1.55
4.80 ± 0.83
5.01 ± 1.44
Creatinine (µmol/L)
72.46 ± 18.80
100.23 ± 41.43
104.68 ± 69.54
98.84 ± 31.74
99.15 ± 27.09
CRP (mg/L)
0.87 ± 0.65
7.71 ± 8.69
6.07 ± 6.79
6.93 ± 7.99
9.87 ± 10.38
CKMB (ng/mL)
1.27 ± 0.81
2.15 ± 1.50
1.84 ± 1.18
2.15 ± 1.34
2.36 ± 1.85
TnI (ng/mL)
0.01 ± 0.01
0.06 ± 0.18
0.04 ± 0.06
0.09 ± 0.26
0.04 ± 0.04
NT-proBNP (pg/mL)
94 ± 84
5053 ± 5590
3513 ± 3074
4980 ± 6092
6179 ± 6040
LVEF (%)
65.33 ± 5.67
29.89 ± 5.94
32.41 ± 4.89
30.20 ± 5.65
27.79 ± 6.36
LVEDD (mm)
46.91 ± 3.60
65.95 ± 7.52
65.27 ± 7.35
66.09 ± 7.39
66.21 ± 7.99
Medications, (%)
ACEI/ARB
0
37 (37)
10 (45.4)
11 (24.4)
16 (48.5)
-blocker
0
19 (19)
8 (36.4)
7 (15.6)
4 (12.1)
Diuretics
0
46 (46)
11 (50)
14 (31.1)
21 (63.6)
Digitalis
0
44 (44.0)
10 (45.4)
13 (28.9)
21 (63.6)
Spironolactone
0
31 (31)
7 (31.8)
12 (26.7)
12 (36.4)
The data are given as the mean ± SD or number of patients. DCM: dilated cardiomyopathy; BMI: body mass index; HR: heart rate; SBP: systolic blood pressure; DBP: diastolic blood pressure; TG: total triglycerides; TC: total cholesterol; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; GLU: fasting glucose; CRP: C-reactive protein; NT-proBNP: N-terminal pro-brain natriuretic peptide; LVEF: left ventricular ejection fraction; LVEDD: left ventricular end-diastolic dimension; ACEI: angiotensin-converting enzyme inhibitor; ARB: angiotensin receptor blocker. versus control.
