Survivin as a Novel Biomarker in the Pathogenesis of Acne Vulgaris and Its Correlation to Insulin-Like Growth Factor-I

Table 1

Serum levels of IGF-I and survivin in the studied groups.

	Control	Active acne	Acne scar
Serum IGF-I (ng/mL)	54.1 ± 21.5	85.4 ± 25.3	110.8 ± 32.3
Serum survivin (pg/mL)	25.2 ± 11.8	41.8 ± 23.9	79.4 ± 35.6

Data are presented as mean ± SD (). and indicate significant changes from control and active acne groups respectively. and † indicate significant change at ; and †† indicate significant change at ; indicates significant change at . There were significant higher serum levels of IGF-I and survivin in acne scar and active acne groups than in the control group.