Table of Contents Author Guidelines Submit a Manuscript
Disease Markers
Volume 2016, Article ID 7067984, 12 pages
http://dx.doi.org/10.1155/2016/7067984
Review Article

Oxidative Stress-Related Biomarkers in Postmenopausal Osteoporosis: A Systematic Review and Meta-Analyses

1Department of Prosthodontics, School and Hospital of Stomatology, Wenzhou Medical University, Wenzhou 325027, China
2Department of Pediatric Dentistry, School and Hospital of Stomatology, Wenzhou Medical University, Wenzhou 325027, China
3Institute of Stomatology, School and Hospital of Stomatology, Wenzhou Medical University, Wenzhou 325027, China

Received 5 April 2016; Accepted 3 July 2016

Academic Editor: Fabrizia Bamonti

Copyright © 2016 Qiaozhen Zhou et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. M. N. Weitzmann and R. Pacifici, “Estrogen deficiency and bone loss: an inflammatory tale,” Journal of Clinical Investigation, vol. 116, no. 5, pp. 1186–1194, 2006. View at Publisher · View at Google Scholar · View at Scopus
  2. J. Iwamoto, Y. Sato, T. Takeda, and H. Matsumoto, “Whole body vibration exercise improves body balance and walking velocity in postmenopausal osteoporotic women treated with alendronate: Galileo and Alendronate Intervention Trail (GAIT),” Journal of Musculoskeletal Neuronal Interactions, vol. 12, no. 3, pp. 136–143, 2012. View at Google Scholar · View at Scopus
  3. D. L. Diab and N. B. Watts, “Postmenopausal osteoporosis,” Current Opinion in Endocrinology, Diabetes and Obesity, vol. 20, no. 6, pp. 501–509, 2013. View at Publisher · View at Google Scholar · View at Scopus
  4. S. Das and J. C. Crockett, “Osteoporosis—a current view of pharmacological prevention and treatment,” Drug Design, Development and Therapy, vol. 7, pp. 435–448, 2013. View at Publisher · View at Google Scholar · View at Scopus
  5. J. A. Kanis and O. Johnell, “Requirements for DXA for the management of osteoporosis in Europe,” Osteoporosis International, vol. 16, no. 3, pp. 229–238, 2005. View at Publisher · View at Google Scholar · View at Scopus
  6. C. Cervellati, G. Bonaccorsi, E. Cremonini et al., “Bone mass density selectively correlates with serum markers of oxidative damage in post-menopausal women,” Clinical Chemistry and Laboratory Medicine, vol. 51, no. 2, pp. 333–338, 2013. View at Publisher · View at Google Scholar · View at Scopus
  7. S. C. Manolagas, “From estrogen-centric to aging and oxidative stress: a revised perspective of the pathogenesis of osteoporosis,” Endocrine Reviews, vol. 31, no. 3, pp. 266–300, 2010. View at Publisher · View at Google Scholar · View at Scopus
  8. S. Yang, D. Feskanich, W. C. Willett, A. H. Eliassen, and T. Wu, “Association between global biomarkers of oxidative stress and hip fracture in postmenopausal women: a prospective study,” Journal of Bone and Mineral Research, vol. 29, no. 12, pp. 2577–2583, 2014. View at Publisher · View at Google Scholar · View at Scopus
  9. J. Flatow, P. Buckley, and B. J. Miller, “Meta-analysis of oxidative stress in schizophrenia,” Biological Psychiatry, vol. 74, no. 6, pp. 400–409, 2013. View at Publisher · View at Google Scholar · View at Scopus
  10. X.-C. Bai, D. Lu, J. Bai et al., “Oxidative stress inhibits osteoblastic differentiation of bone cells by ERK and NF-κB,” Biochemical and Biophysical Research Communications, vol. 314, no. 1, pp. 197–207, 2004. View at Publisher · View at Google Scholar · View at Scopus
  11. N. Mody, F. Parhami, T. A. Sarafian, and L. L. Demer, “Oxidative stress modulates osteoblastic differentiation of vascular and bone cells,” Free Radical Biology and Medicine, vol. 31, no. 4, pp. 509–519, 2001. View at Publisher · View at Google Scholar · View at Scopus
  12. M. Almeida, L. Han, M. Martin-Millan et al., “Skeletal involution by age-associated oxidative stress and its acceleration by loss of sex steroids,” The Journal of Biological Chemistry, vol. 282, no. 37, pp. 27285–27297, 2007. View at Publisher · View at Google Scholar · View at Scopus
  13. M. A. Sánchez-Rodríguez, M. Ruiz-Ramos, E. Correa-Muñoz, and V. M. Mendoza-Núñez, “Oxidative stress as a risk factor for osteoporosis in elderly Mexicans as characterized by antioxidant enzymes,” BMC Musculoskeletal Disorders, vol. 8, article 124, 2007. View at Publisher · View at Google Scholar · View at Scopus
  14. S. Basu, K. Michaëlsson, H. Olofsson, S. Johansson, and H. Melhus, “Association between oxidative stress and bone mineral density,” Biochemical and Biophysical Research Communications, vol. 288, no. 1, pp. 275–279, 2001. View at Publisher · View at Google Scholar · View at Scopus
  15. D. Maggio, M. Barabani, M. Pierandrei et al., “Marked decrease in plasma antioxidants in aged osteoporotic women: results of a cross-sectional study,” Journal of Clinical Endocrinology and Metabolism, vol. 88, no. 4, pp. 1523–1527, 2003. View at Publisher · View at Google Scholar · View at Scopus
  16. A. N. Sontakke and R. S. Tare, “A duality in the roles of reactive oxygen species with respect to bone metabolism,” Clinica Chimica Acta, vol. 318, no. 1-2, pp. 145–148, 2002. View at Publisher · View at Google Scholar · View at Scopus
  17. S. Yalin, S. Bagis, S. C. Aksit, H. Arslan, and C. Erdogan, “Effect of free radicals and antioxidants on postmenopausal osteoporosis,” Asian Journal of Chemistry, vol. 18, no. 2, pp. 1091–1096, 2006. View at Google Scholar · View at Scopus
  18. S. Ozgocmen, H. Kaya, E. Fadillioglu, and Z. Yilmaz, “Effects of calcitonin, risedronate, and raloxifene on erythrocyte antioxidant enzyme activity, lipid peroxidation, and nitric oxide in postmenopausal osteoporosis,” Archives of Medical Research, vol. 38, no. 2, pp. 196–205, 2007. View at Publisher · View at Google Scholar · View at Scopus
  19. I. Dalle-Donne, R. Rossi, R. Colombo, D. Giustarini, and A. Milzani, “Biomarkers of oxidative damage in human disease,” Clinical Chemistry, vol. 52, no. 4, pp. 601–623, 2006. View at Publisher · View at Google Scholar · View at Scopus
  20. C. N. Black, M. Bot, P. G. Scheffer, P. Cuijpers, and B. W. J. H. Penninx, “Is depression associated with increased oxidative stress? A systematic review and meta-analysis,” Psychoneuroendocrinology, vol. 51, pp. 164–175, 2015. View at Publisher · View at Google Scholar · View at Scopus
  21. O. Altindag, O. Erel, N. Soran, H. Celik, and S. Selek, “Total oxidative/anti-oxidative status and relation to bone mineral density in osteoporosis,” Rheumatology International, vol. 28, no. 4, pp. 317–321, 2008. View at Publisher · View at Google Scholar · View at Scopus
  22. N. Yilmaz and E. Eren, “Homocysteine oxidative stress and relation to bone mineral density in post-menopausal osteoporosis,” Aging Clinical and Experimental Research, vol. 21, no. 4-5, pp. 353–357, 2009. View at Publisher · View at Google Scholar · View at Scopus
  23. G. Yousefzadeh, B. Larijani, A. Mohammadirad et al., “Determination of oxidative stress status and concentration of TGF-β1 in the blood and saliva of osteoporotic subjects,” Annals of the New York Academy of Sciences, vol. 1091, pp. 142–150, 2006. View at Publisher · View at Google Scholar · View at Scopus
  24. V. Akpolat, H. M. Bilgin, M. Y. Celik, M. Erdemoglu, and B. Isik, “An evaluation of nitric oxide, folate, homocysteine levels and lipid peroxidation in postmenopausal osteoporosis,” Advances in Clinical and Experimental Medicine, vol. 22, no. 3, pp. 403–409, 2013. View at Google Scholar · View at Scopus
  25. O. F. Sendur, Y. Turan, E. Tastaban, and M. Serter, “Antioxidant status in patients with osteoporosis: a controlled study,” Joint Bone Spine, vol. 76, no. 5, pp. 514–518, 2009. View at Publisher · View at Google Scholar · View at Scopus
  26. M. Zinnuroglu, A. S. Dincel, F. Kosova, V. Sepici, and G. K. Karatas, “Prospective evaluation of free radicals and antioxidant activity following 6-month risedronate treatment in patients with postmenopausal osteoporosis,” Rheumatology International, vol. 32, no. 4, pp. 875–880, 2012. View at Publisher · View at Google Scholar · View at Scopus
  27. Z. Ouzzif, K. Oumghar, K. Sbai, A. Mounach, E. M. Derouiche, and A. El Maghraoui, “Relation of plasma total homocysteine, folate and vitamin B12 levels to bone mineral density in Moroccan healthy postmenopausal women,” Rheumatology International, vol. 32, no. 1, pp. 123–128, 2012. View at Publisher · View at Google Scholar · View at Scopus
  28. N. Bozkurt, M. Erdem, E. YIlmaz et al., “The relationship of homocyteine, B12 and folic acid with the bone mineral density of the femur and lumbar spine in Turkish postmenopausal women,” Archives of Gynecology and Obstetrics, vol. 280, no. 3, pp. 381–387, 2009. View at Publisher · View at Google Scholar · View at Scopus
  29. B. Haliloglu, F. B. Aksungar, E. Ilter, H. Peker, F. T. Akin, and U. Ozekici, “Relationship between bone mineral density, bone turnover markers and homocysteine, folate and vitamin B12 levels in postmenopausal women,” Archives of Gynecology and Obstetrics, vol. 281, no. 4, pp. 663–668, 2010. View at Publisher · View at Google Scholar · View at Scopus
  30. M. Baines, M.-B. Kredan, J. Usher et al., “The association of homocysteine and its determinants MTHFR genotype, folate, vitamin B12 and vitamin B6 with bone mineral density in postmenopausal British women,” Bone, vol. 40, no. 3, pp. 730–736, 2007. View at Publisher · View at Google Scholar · View at Scopus
  31. A. Cagnacci, F. Baldassari, G. Rivolta, S. Arangino, and A. Volpe, “Relation of homocysteine, folate, and vitamin B12 to bone mineral density of postmenopausal women,” Bone, vol. 33, no. 6, pp. 956–959, 2003. View at Publisher · View at Google Scholar · View at Scopus
  32. T. Sharma, N. Islam, J. Ahmad, N. Akhtar, and M. Beg, “Correlation between bone mineral density and oxidative stress in postmenopausal women,” Indian Journal of Endocrinology and Metabolism, vol. 19, no. 4, pp. 491–497, 2015. View at Publisher · View at Google Scholar
  33. Q. Wu, Z.-M. Zhong, Y. Pan et al., “Advanced oxidation protein products as a novel marker of oxidative stress in postmenopausal osteoporosis,” Medical Science Monitor, vol. 21, pp. 2428–2432, 2015. View at Publisher · View at Google Scholar · View at Scopus
  34. C. Cervellati, G. Bonaccorsi, E. Cremonini et al., “Oxidative stress and bone resorption interplay as a possible trigger for postmenopausal osteoporosis,” BioMed Research International, vol. 2014, Article ID 569563, 8 pages, 2014. View at Publisher · View at Google Scholar · View at Scopus
  35. X. Wang, W. Wang, L. Li, G. Perry, H.-G. Lee, and X. Zhu, “Oxidative stress and mitochondrial dysfunction in Alzheimer's disease,” Biochimica et Biophysica Acta (BBA)—Molecular Basis of Disease, vol. 1842, no. 8, pp. 1240–1247, 2014. View at Publisher · View at Google Scholar · View at Scopus
  36. H. Sies, “Strategies of antioxidant defense,” European Journal of Biochemistry, vol. 215, no. 2, pp. 213–219, 1993. View at Publisher · View at Google Scholar · View at Scopus
  37. N. I. Krinsky, “Mechanism of action of biological antioxidants,” Proceedings of the Society for Experimental Biology and Medicine, vol. 200, no. 2, pp. 248–254, 1992. View at Publisher · View at Google Scholar · View at Scopus
  38. C. Michiels, M. Raes, O. Toussaint, and J. Remacle, “Importance of se-glutathione peroxidase, catalase, and Cu/Zn-SOD for cell survival against oxidative stress,” Free Radical Biology and Medicine, vol. 17, no. 3, pp. 235–248, 1994. View at Publisher · View at Google Scholar · View at Scopus
  39. R. J. van't Hof and S. H. Ralston, “Nitric oxide and bone,” Immunology, vol. 103, no. 3, pp. 255–261, 2001. View at Publisher · View at Google Scholar · View at Scopus
  40. J. Aguirre, L. Buttery, M. O'Shaughnessy et al., “Endothelial nitric oxide synthase gene-deficient mice demonstrate marked retardation in postnatal bone formation, reduced bone volume, and defects in osteoblast maturation and activity,” The American Journal of Pathology, vol. 158, no. 1, pp. 247–257, 2001. View at Publisher · View at Google Scholar · View at Scopus
  41. M. S. Leboff, R. Narweker, A. Lacroix et al., “Homocysteine levels and risk of hip fracture in postmenopausal women,” The Journal of Clinical Endocrinology & Metabolism, vol. 94, no. 4, pp. 1207–1213, 2009. View at Publisher · View at Google Scholar · View at Scopus
  42. R. R. McLean, P. F. Jacques, J. Selhub et al., “Homocysteine as a predictive factor for hip fracture in older persons,” The New England Journal of Medicine, vol. 350, no. 20, pp. 2042–2049, 2004. View at Publisher · View at Google Scholar · View at Scopus
  43. J. B. J. van Meurs, R. A. M. Dhonukshe-Rutten, S. M. F. Pluijm et al., “Homocysteine levels and the risk of osteoporotic fracture,” The New England Journal of Medicine, vol. 350, no. 20, pp. 2033–2041, 2004. View at Publisher · View at Google Scholar · View at Scopus
  44. M. S. Morris, P. F. Jacques, and J. Selhub, “Relation between homocysteine and B-vitamin status indicators and bone mineral density in older Americans,” Bone, vol. 37, no. 2, pp. 234–242, 2005. View at Publisher · View at Google Scholar · View at Scopus
  45. J. Golbahar, A. Hamidi, M. A. Aminzadeh, and G. R. Omrani, “Association of plasma folate, plasma total homocysteine, but not methylenetetrahydrofolate reductase C667T polymorphism, with bone mineral density in postmenopausal Iranian women: a cross-sectional study,” Bone, vol. 35, no. 3, pp. 760–765, 2004. View at Publisher · View at Google Scholar · View at Scopus
  46. H. Zhang, X. Tao, and J. Wu, “Association of homocysteine, vitamin B12, and folate with bone mineral density in postmenopausal women: a meta-analysis,” Archives of Gynecology and Obstetrics, vol. 289, no. 5, pp. 1003–1009, 2014. View at Publisher · View at Google Scholar · View at Scopus
  47. P. Gerdhem, K. K. Ivaska, A. Isaksson et al., “Associations between homocysteine, bone turnover, BMD, mortality, and fracture risk in elderly women,” Journal of Bone and Mineral Research, vol. 22, no. 1, pp. 127–134, 2007. View at Publisher · View at Google Scholar · View at Scopus
  48. P. Bucciarelli, G. Martini, I. Martinelli et al., “The relationship between plasma homocysteine levels and bone mineral density in post-menopausal women,” European Journal of Internal Medicine, vol. 21, no. 4, pp. 301–305, 2010. View at Publisher · View at Google Scholar · View at Scopus
  49. M. A. Périer, E. Gineyts, F. Munoz, E. Sornay-Rendu, and P. D. Delmas, “Homocysteine and fracture risk in postmenopausal women: the OFELY study,” Osteoporosis International, vol. 18, no. 10, pp. 1329–1336, 2007. View at Publisher · View at Google Scholar · View at Scopus