ACE Gene I/D Polymorphism and Obesity in 1,574 Patients with Type 2 Diabetes Mellitus

Table 5

Clinical and biochemical characteristics of Chinese patients with type 2 diabetes relating to BMI.

	Lean	Normal	Overweight	Obese	P	P	P
Patients ()	58	631	279	606	—	—	—
M : F	22 : 36	185 : 276	165 : 207	266 : 417	—	—	—
Age (years)					0.021	0.797	0.012
BMI (kg/m^2)					<0.001	<0.001	<0.001
WHR					<0.001	<0.001	<0.001
FPG (mmol/L)					0.074	0.594	0.198
(%)					0.093	0.192	0.086
TC (mmol/L)					0.179	0.001	0.003
TG (mmol/L)					0.224	<0.001	<0.001
LDL-C (mmol/L)					0.828	0.035	0.025
HDL-C (mmol/L)					<0.001	0.002	<0.001
SBP (mmHg)					0.001	0.012	0.037
DBP (mmHg)					0.015	0.001	<0.001
MAP (mmHg)					0.002	0.002	<0.001
PP (mmHg)					0.004	0.223	0.260

Data are shown as means ± SD. P value is derived by analysis of variance (ANOVA).
P values compared normal group with lean group.
P values compared normal group with overweight group.
P values compared normal group with obese group.
BMI: body mass index; WHR: waist-to-hip ratio; FPG: fasting plasma glucose; : glycated hemoglobin; TC: total cholesterol; TG: triglycerides; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; SBP: systolic blood pressure; DBP: diastolic blood pressure; MAP: mean arterial pressure; PP: pulse pressure.