The Serum Concentrations of Chemokine CXCL12 and Its Specific Receptor CXCR4 in Patients with Esophageal Cancer

Table 3

Diagnostic criteria for chemokine CXCL12 and its receptor (CXCR4), classical tumor markers (CEA and SCC-Ag), and C-reactive protein (CRP) levels in esophageal cancer (EC) patients.

	Diagnostic sensitivity	Diagnostic specificity	Positive predictive value	Negative predictive value	Diagnostic accuracy
CXCL12	47	80	79	48	59
CXCR4	80	57	75	63	71
CEA	22	93	85	42	49
SCC-Ag	14	97	88	41	46
CRP	57	97	97	58	72
CXCL12 + CXCR4	94	37	71	79	72
CEA + SCC-Ag	33	90	84	45	54
CXCL12 + CRP	73	80	86	65	76
CXCL12 + CEA	59	77	81	53	66
CXCL12 + SCC-Ag	59	77	81	53	66
CXCR4 + CRP	92	53	76	80	77
CXCR4 + CEA	84	53	75	67	72
CXCR4 + SCC-Ag	82	53	74	64	71