Expression Pattern and Clinicopathological Relevance of the Indoleamine 2,3-Dioxygenase 1/Tryptophan 2,3-Dioxygenase Protein in Colorectal Cancer

Table 4

Correlation of IDO1 and TDO2 expression and gene mutations of CRC patients.

Genes	IDO1		TDO2
	Low	High	Low	High
APC
Wild type (57.6%)	48	51	48	51
Mutant (42.4%)	30	43	31	42
value	0.356		0.444
TP53
Wild type (82.0%)	60	81	66	75
Mutant (18.0%)	18	13	13	18
value	0.162		0.693
KRAS
Wild type (78.5%)	60	75	59	76
Mutant (21.5%)	19	19	21	17
value	0.583		0.269