Research Article

The Effect of Poly(ADP-ribose) Polymerase-1 Gene 3′Untranslated Region Polymorphism in Colorectal Cancer Risk among Saudi Cohort

Table 6

Allele frequencies of PARP-1 SNP rs8679 in Saudi and other populations.

PopulationNumber of samplesFreq. of “T”Freq. of “C” value value

CEU2260.22 (49)0.78 (177)3.7617210.052439
JPT1720.08 (13)0.92 (159)29.14925<0.00001
YRI2260.02 (4)0.98 (222)66.0301<0.00001
ASW980.07 (7)0.93 (91)19.54286<0.00001
CHB820.05 (4)0.95 (78)20.77929<0.00001
CHD1700.06 (11)0.94 (159)32.42167<0.00001
GIH1760.26 (45)0.74 (131)0.8927030.344746
LWK1800.01 (1)0.99 (179)60.63121<0.00001
MEX1000.15 (15)0.85 (85)7.8985090.004948
MKK2860.04 (12)0.96 (274)61.30637<0.00001
TSI1760.34 (60)0.66 (116)0.7030750.401752
SAUDI1900.3 (57)0.7 (133)Ref

CEU = Utah residents with northern and western European ancestry from the CEPH collection; JPT = Japanese in Tokyo, Japan; YRI = Yoruba in Ibadan, Nigeria; ASW = African ancestry in southwest USA; CHB = Han Chinese in Beijing, China = CHD; GIH = Gujarati Indians in Houston, Texas; LWK = Luhya in Webuye, Kenya; MEX = Mexican ancestry in Los Angeles, California; MKK = Maasai in Kinyawa, Kenya; TSI = Tuscans in Italy; SAUDI = Saudi population residing in Riyadh region.