Is GERD a Factor in Osteonecrosis of the Jaw? Evidence of Pathology Linked to G6PD Deficiency and Sulfomucins

Table 3

Evidence that ONJ is linked to Sjögren’s syndrome. Both the syndrome itself and the various conditions associated with the syndrome are all overrepresented in association with ONJ compared to NOT ONJ, some by a wide margin of significance.

Side effect	Count 1	Count 2	f1/f2	Score
Sialoadenitis	103	209	34.7	972
Vulvovaginal dryness	121	444	19.4	951
% Sjögren’s	85	531	11.5	920
Dry eye	331	2796	8.5	895
% lymphoma	196	2289	6.1	860
Dry mouth	608	7289	6.0	857
Dry skin	129	5290	1.8	637
Total count	10580	762002	1.0	500