Table 7: The set of symptom classes that were overrepresented by at least a factor of 3 in the B AND G group compared to the predicted occurrence based on the B NOT G group and the G NOT B group. B: bisphosphonates; G: GERD. As indicated, “MUCOSA” was a substring match, and everything else required exact match. Computation of the score is defined in (1) and computation of the bias is defined in (2).

Side effect/f0/f0/f0Bias

Osteonecrosis of jaw90515966195.85
Bone marrow oedema85820494310.68
Anhedonia6604288513.93
% mucosa7385959413.85
Sialoadenitis8843959493.74
Lymphoedema8095469503.73
Oedema6336759153.00