Research Article
Analysis of Urinary Prostate-Specific Antigen Glycoforms in Samples of Prostate Cancer and Benign Prostate Hyperplasia
Table 5
Areas under the ROC curves of the target PSA glycopeptides.
| Glycan composition | AUC | value | Cancer threshold | Sensitivity | Specificity |
| H5N4S1F1 | 0.7381 ± 0.0661 | 0.009 | <0.470 | 92.9% | 59.0% | Monosialylated | 0.7102 ± 0.0681 | 0.015 | <1.060 | 100% | 47.5% | Sialylated | 0.6938 ± 0.0763 | 0.025 | <1.260 | 68.8% | 75% | Unfucosylated | 0.6758 ± 0.0699 | 0.041 | <1.065 | 87.5% | 60% | Total | 0.7242 ± 0.0662 | 0.009 | <1.815 | 87.5% | 60% |
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AUC was calculated based on the samples which could be detected for the indicated glycoform or grouped glycoforms.
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