Association of lincRNA-p21 Haplotype with Coronary Artery Disease in a Chinese Han Population
Table 5
Association between lincRNA-p21 gene haplotypes with the risk of premature CAD/MI.
Haplotype
Controls
Cases
OR (95% CI)
P
Number (%)
Number (%)
Premature CAD
AAAG
63.00 (10.2)
56.77 (11.9)
1.20 (0.82–1.76)
0.344
GAAG
118.99 (19.3)
65.29 (13.7)
0.67 (0.48–0.93)
GAGA
111.00 (18.0)
95.23 (20.0)
1.15 (0.85–1.56)
0.364
GAGG
193.01 (31.2)
167.71 (35.2)
1.21 (0.94–1.56)
0.142
GGGA
131.99 (21.4)
88.06 (18.5)
0.84 (0.62–1.14)
0.263
Premature MI
AAAG
63.00 (10.2)
29.68 (11.5)
1.17 (0.73–1.85)
0.514
GAAG
118.99 (19.3)
34.16 (13.2)
0.65 (0.43–0.99)
0.041
GAGA
111.00 (18.0)
44.31 (17.2)
0.97 (0.66–1.42)
0.859
GAGG
193.01 (31.2)
96.85 (37.5)
1.36 (1.00–1.84)
0.049
GGGA
131.99 (21.4)
48.84 (18.9)
0.88 (0.61–1.27)
0.484
The allelic sequence in the haplotypes is in the following order: rs9380586, rs4713998, rs6930083, rs6931097. Haplotype with frequency less than 3% was pooled and not analyzed. P values under 0.05 were shown in bold font.
