Research Article

Identification of Factors for the Preoperative Prediction of Tumour Subtype and Prognosis in Patients with T1 Lung Adenocarcinoma

Table 1

Characteristics of the patients and tumours.

VariableCategoryNumber (%)

SexMale38 (43.7)
Female49 (56.3)

Median age (range) (27–81)

SmokingCurrent smoker66 (75.9)
Never smoked21 (24.1)

Radiological findingPure GGO19 (21.8)
Mixed GGO51 (58.6)
Pure solid nodule17 (19.6)

CEA≤5 ng/mL74 (85.1)
>5 ng/mL13 (14.9)

Serum miR-183≤1.0 ()43 (49.4)
>1.0 ()44 (50.6)

Tumour size≤10 mm42 (48.3)
>10 to ≤20 mm30 (34.5)
>21 to ≤30 mm15 (17.2)

Nodule numberSingle82 (94.3)
Multiple5 (5.7)

Predominant subtypeAIS19 (21.8)
MIA22 (25.3)
Lepidic-predominant IAC11 (12.7)
Papillary-predominant IAC23 (26.4)
Acinar-predominant IAC9 (10.3)
Solid-predominant IAC2 (2.3)
Invasive mucinous IAC1 (1.2)

Lymph node metastasisPresent4 (4.6)

Visceral pleural invasionPresent9 (10.3)

Pathological stage05 (5.7)
I76 (87.4)
II4 (4.6)
III2 (2.3)

CEA, carcinoembryonic antigen; GGO, ground-glass opacity; AIS, adenocarcinoma in situ; MIA, minimally invasive adenocarcinoma; IAC, invasive adenocarcinoma.