Expression Status of PIWIL1 as a Prognostic Marker of Colorectal Cancer

Table 3

Cox regression analysis of OS and DFS in 110 patients with colorectal cancer.

Characteristics	DFS			OS
	HR	95% CI	^a	HR	95% CI	^a
TNM stage			0.048			0.031
I
II	1.316	0.265–6.545	0.737	1.064	0.210–5.382	0.940
III	3.323	0.761–14.514	0.110	3.007	0.702–12.876	0.138
IV	4.510	1.906–12.462	0.046	4.502	1.915–12.146	0.044
Differentiation			<0.001			<0.001
Well
Moderate	0.808	0.260–2.511	0.713	0.828	0.268–2.558	0.743
Poor	4.151	1.941–9.493	0.002	4.401	2.017–10.315	0.002
Lymphovascular invasion			0.006			0.009
No
Yes	2.756	1.606–8.082		2.029	1.714–9.750
PIWIL1 expression			0.002			0.005
Low
High	3.227	1.563–6.662		2.803	1.374–5.717

OS: overall survival; DFS: disease-free survival; HR: hazard ratio; CI: confidence interval; TNM: tumor node metastasis; ^aCox regression test.