Research Article
Expression of Autophagy-Related Proteins in Hürthle Cell Neoplasm Is Different from That in Follicular Neoplasm
Table 3
Expression of autophagy-related proteins in follicular adenomas, follicular carcinomas, Hürthle cell adenomas, and Hürthle cell carcinomas.
| | Parameters | Follicular neoplasm
(%) | Hürthle cell neoplasm
(%) | value | FA
(%) | FC
(%) | HCA
(%) | HCC
(%) |
| | Beclin-1 | | | | | <0.001 | | Negative | 153 (100.0) | 112 (100.0) | 74 (91.4) | 18 (66.7) | | | Positive | 0 (0.0) | 0 (0.0) | 7 (8.6) | 9 (33.3) | | | LC3A | | | | | 0.411 | | Negative | 141 (92.2) | 99 (88.4) | 77 (95.1) | 25 (92.6) | | | Positive | 12 (7.8) | 13 (11.6) | 4 (4.9) | 2 (7.4) | | | LC3B | | | | | <0.001 | | Negative | 153 (100.0) | 112 (100.0) | 31 (38.1) | 2 (7.4) | | | Positive | 0 (0.0) | 0 (0.0) | 50 (61.7) | 25 (92.6) | | | p62 | | | | | <0.001 | | Negative | 85 (55.6) | 53 (47.3) | 2 (2.5) | 3 (11.1) | | | Positive | 68 (44.4) | 59 (52.7) | 79 (97.5) | 24 (88.9) | | | BNIP3 | | | | | <0.001 | | Negative | 146 (95.4) | 107 (95.5) | 37 (45.7) | 4 (14.8) | | | Positive | 7 (4.6) | 5 (4.5) | 44 (54.3) | 23 (85.2) | |
|
|
FA: follicular adenoma; FC: follicular carcinoma; HCA: Hürthle cell adenoma; HCC: Hürthle cell carcinoma.
|
