Research Article
Relationship between rs854560 PON1 Gene Polymorphism and Tobacco Smoking with Coronary Artery Disease
Table 1
Clinical and biochemical characteristics of coronary artery disease patient (CAD) and blood donor (BD) groups.
| | Characteristics | CAD
| BD
| OR
(95% CI) | |
| | Age (years), mean ± SD | 44.58 ± 5.98 | 43.58 ± 6.32 | — | NS | | Male gender, n (%) | 173 (69.76) | 175 (71.14) | 0.94 (0.64–1.38) | NS | | TC (mmol/L), mean ± SD | 5.80 ± 1.35 | 5.09 ± 1.21 | — | <10−6 | | HDL (mmol/L), mean ± SD | 1.12 ± 0.37 | 1.45 ± 0.56 | — | <10−6 | | LDL (mmol/L), mean ± SD | 3.88 ± 1.18 | 2.99 ± 1.22 | — | <10−6 | | TG (mmol/L), mean ± SD | 1.86 ± 0.97 | 1.37 ± 0.72 | — | <10−6 | | BMI ± SD | 27.11 ± 4.24 | 26.15 ± 3.84 | — | 0.01 | | Familial history of CAD, n (%) | 88 (50.57) | — | 2.54 (2.25–2.86) | <10−8 | | Diabetes mellitus, n (%) | 22 (8.98) | — | 2.09 (1.90–2.29) | <10−8 | | Hypertension, n (%) | 138 (57.26) | — | 3.24 (2.77–3.78) | <10−8 | | Smoking, n (%) | 146 (68.54) | 67 (31.46) | 3.82 (2.62–5.58) | <10−7 |
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NS: not statistically significant; OR: odds ratio; SD: standard deviation; TC: total cholesterol; HDL: high-density lipoprotein; LDL: low-density lipoprotein; TG: triglycerides; BMI: body mass index. Univariate analysis. Risk ratio values (95% CI), univariate analysis.
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