Research Article
Relationship between rs854560 PON1 Gene Polymorphism and Tobacco Smoking with Coronary Artery Disease
Table 5
PON1 rs854560 polymorphism genotype and allele frequencies in smoker and nonsmoker groups.
| Genotype/allele | Smokers (%) | Nonsmokers (%) | Model of inheritance | OR (95% CI) | |
| AA | 80 (39.80) | 108 (43.72) | Dominant versus AT + TT | 0.85 (0.58–1.24) | NS | AT | 98 (48.76) | 111 (44.94) | Additive versus AA | 1.19 (0.80–1.77) | NS | TT | 23 (11.44) | 28 (11.34) | Additive versus AA | 1.11 (0.59–2.07) | NS | versus AA + AT | 1.01 (0.56–1.82) | NS | AA + AT | 178 (88.56) | 219 (88.66) | Recessive versus TT | 0.99 (0.55–1.78) | NS | A | 258 (64.18) | 327 (66.19) | — | 0.92 (0.69–1.21) | NS | T | 144 (35.82) | 167 (33.81) | — | 1.09 (0.83–1.44) | NS |
|
|
NS: not statistically significant; OR: odds ratio.
|