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Disease Markers
Volume 2017, Article ID 1575374, 12 pages
https://doi.org/10.1155/2017/1575374
Research Article

Heat Shock Protein HSP27 Secretion by Ovarian Cancer Cells Is Linked to Intracellular Expression Levels, Occurs Independently of the Endoplasmic Reticulum Pathway and HSP27’s Phosphorylation Status, and Is Mediated by Exosome Liberation

1Department of Urology, University Medicine Greifswald, Ferdinand-Sauerbruch-Strasse, 17475 Greifswald, Germany
2Department of Gynaecology and Obstetrics, University Medicine Greifswald, Ferdinand-Sauerbruch-Strasse, 17475 Greifswald, Germany

Correspondence should be addressed to Matthias B. Stope; ed.dlawsfierg-inu@epots.saihttam

Received 22 September 2016; Revised 6 February 2017; Accepted 12 February 2017; Published 23 February 2017

Academic Editor: Lance A. Liotta

Copyright © 2017 Matthias B. Stope et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [3 citations]

The following is the list of published articles that have cited the current article.

  • V. Sudhakar Reddy, Satish K. Madala, Jamma Trinath, and G. Bhanuprakash Reddy, “Extracellular small heat shock proteins: exosomal biogenesis and function,” Cell Stress and Chaperones, 2017. View at Publisher · View at Google Scholar
  • Atefe Abak, Alireza Abhari, and Sevda Rahimzadeh, “Exosomes in cancer: small vesicular transporters for cancer progression and metastasis, biomarkers in cancer therapeutics,” PeerJ, vol. 6, pp. e4763, 2018. View at Publisher · View at Google Scholar
  • Margaux Sevin, Lucia Kubovcakova, Nicolas Pernet, Sébastien Causse, Franck Vitte, Jean Luc Villeval, Catherine Lacout, Marine Cordonnier, Fernando Rodrigues-Lima, Gaétan Chanteloup, Matthieu Mosca, Marie-Lorraine Chrétien, Jean Noël Bastie, Sylvain Audia, Paul Sagot, Selim Ramla, Laurent Martin, Martin Gleave, Valérie Mezger, Radek Skoda, Isabelle Plo, Carmen Garrido, François Girodon, and Aurélie de Thonel, “HSP27 is a partner of JAK2-STAT5 and a potential therapeutic target in myelofibrosis,” Nature Communications, vol. 9, no. 1, 2018. View at Publisher · View at Google Scholar