FRAX® Fracture Risks Are Associated with Coronary Artery Calcification Score
Table 1
Demographic and clinical characteristics of study participants.
All
Male
Female
value
Number
81
51
30
Age (range) (years)
55.8 ± 9.9 (27–81)
55.1 ± 10.6 (27–81)
57.1 ± 8.6 (34–75)
0.379
Height (cm)
164.0 ± 8.2
168.3 ± 6.8
156.6 ± 4.2
<0.001
Weight (kg)
67.9 ± 12.3
73.1 ± 11.2
59.0 ± 8.5
<0.001
BMI (kg/m2)
25.1 ± 3.2
25.7 ± 3.0
24.1 ± 3.5
0.029
Smoking (%)
6 (7.4)
6 (11.8)
0 (0.0)
0.080
Drinking (%)
4 (4.9)
4 (7.8)
0 (0.0)
0.291
Hypertension (%)
19 (23.5)
10 (19.6)
9 (30.0)
0.286
Diabetes mellitus (%)
9 (11.1)
7 (13.7)
2 (6.7)
0.473
Hyperlipidemia (%)
5 (6.2)
3 (5.9)
2 (6.7)
>0.999
Secondary osteoporosis (%)
14 (17.3)
8 (15.7)
6 (20.0)
0.620
TC (mg/dL)
189.1 ± 32.7
183.1 ± 32.3
199.3 ± 31.3
0.031
LDL-C (mg/dL)
121.6 ± 27.5
116.8 ± 30.1
129.7 ± 20.4
0.025
HDL-C (mg/dL)
48.6 ± 15.0
43.7 ± 10.7
57.0 ± 17.5
<0.001
Triglycerides (mg/dL)
145.2 ± 95.5
166.0 ± 109.0
109.8 ± 51.1
0.002
Glucose (mg/dL)
107.4 ± 20.8
110.1 ± 24.5
102.8 ± 11.0
0.073
SBP (mmHg)
126.0 ± 22.9
127.2 ± 18.3
124.1 ± 29.4
0.606
DBP (mmHg)
78.7 ± 15.4
81.7 ± 15.4
73.7 ± 14.1
0.022
Lumbar spine BMD (g/cm2)
0.969 ± 0.139
1.011 ± 0.129
0.898 ± 0.129
<0.001
Lumbar spine T-score
−0.63 ± 1.21
−0.33 ± 1.16
−1.12 ± 1.14
0.004
Right neck BMD (g/cm2)
0.732 ± 0.118
0.769 ± 0.123
0.669 ± 0.075
<0.001
Right neck T-score
−1.04 ± 0.95
−0.81 ± 1.00
−1.41 ± 0.74
0.006
Right total BMD (g/cm2)
0.838 ± 0.141
0.874 ± 0.128
0.778 ± 0.144
0.003
Right total T-score
−0.42 ± 0.93
−0.37 ± 0.84
−0.51 ± 1.08
0.492
Left neck BMD (g/cm2)
0.738 ± 0.122
0.772 ± 0.121
0.682 ± 0.105
0.001
Left neck T-score
−1.01 ± 0.99
−0.78 ± 1.00
−1.39 ± 0.87
0.007
Left total BMD (g/cm2)
0.840 ± 0.139
0.882 ± 0.118
0.768 ± 0.143
<0.001
Left total T-score
−0.41 ± 0.91
−0.30 ± 0.83
−0.59 ± 1.01
0.166
Right MOF (FRAX) (%)
4.84 ± 2.87
4.03 ± 2.18
6.21 ± 3.37
0.003
Right HF (FRAX) (%)
1.39 ± 1.62
1.27 ± 1.59
1.60 ± 1.68
0.379
Left MOF (FRAX) (%)
4.88 ± 3.11
3.99 ± 2.35
6.39 ± 3.66
0.002
Left HF (FRAX) (%)
1.41 ± 1.74
1.22 ± 1.69
1.73 ± 1.80
0.207
CAC score
123.8 ± 294.2
137.1 ± 315.0
101.1 ± 258.7
0.598
BMI: body mass index; TC: total cholesterol; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; SBP: systolic blood pressure; DBP: diastolic blood pressure; BMD: bone mineral density; MOF: 10-year probability of a major osteoporotic fracture; HF: 10-year probability of a hip fracture; FRAX: fracture risk assessment tool; TBS: trabecular bone score; CAC score: coronary artery calcification score. Data are expressed as mean ± standard deviation, unless otherwise specified.
