Research Article
Association between Two Resistin Gene Polymorphisms and Metabolic Syndrome in Jilin, Northeast China: A Case-Control Study
Table 3
Genotype distribution by different inheritance models and odds ratio estimate.
| SNP | Genotype | Inheritance model | Case | Control | Adjusted OR (95% CI) | |
| rs1862513 | C/C | Codominant | 191 (10.8%) | 218 (10.8%) | 1 | 0.96 | G/G | | 800 (45.2%) | 918 (45.4%) | 0.98 (0.79–1.21) | G/C | | 780 (44%) | 885 (43.8%) | 0.99 (0.80–1.23) | C/C | Dominant | 191 (10.8%) | 218 (10.8%) | 1 | 0.88 | G/G-C/G | | 1580 (89.2%) | 1803 (89.2%) | 0.98 (0.80–1.21) | C/C-G/G | Recessive | 991 (56%) | 1136 (56.2%) | 1 | 0.86 | G/C | | 780 (44%) | 885 (43.8%) | 1.01 (0.89–1.15) | C/C-G/C | Overdominant | 971 (54.8%) | 1103 (54.6%) | 1 | 0.78 | G/G | | 800 (45.2%) | 918 (45.4%) | 0.98 (0.86–1.12) |
| rs3745368 | G/G | Codominant | 1304 (73.6%) | 1471 (72.8%) | 1 | 0.84 | A/A | | 33 (1.9%) | 37 (1.8%) | 0.97 (0.60–1.57) | A/G | | 434 (24.5%) | 513 (25.4%) | 0.96 (0.82–1.11) | G/G | Dominant | 1304 (73.6%) | 1471 (72.8%) | 1 | 0.56 | A/A-A/G | | 467 (26.4%) | 550 (27.2%) | 0.96 (0.83–1.11) | G/G-A/A | Recessive | 1337 (75.5%) | 1508 (74.6%) | 1 | 0.56 | A/G | | 434 (24.5%) | 513 (25.4%) | 0.96 (0.83–1.11) | G/G-A/G | Overdominant | 1738 (98.1%) | 1984 (98.2%) | 1 | 0.95 | A/A | | 33 (1.9%) | 37 (1.8%) | 0.98 (0.61–1.59) |
|
|
OR: odds ratio; CI: confidence interval. Adjusted for age, sex, smoking status, and alcohol status.
|