Research Article

Diagnostic Value of Autoantibodies against Ezrin in Esophageal Squamous Cell Carcinoma

Table 4

Relationship between positive rate of the autoantibody and clinicopathologic features in ESCC patients.

GroupPositive (%) value

Patient age
 ≤555711 (19.3%)0.077
 >559230 (32.6%)
Patient gender
 Female4212 (28.6%)0.857
 Male10729 (27.1%)
Tumor invasion Depth
 T1 + T23210 (31.3%)0.599
 T3 + T411330 (26.5%)
Lymph node metastasis
 Positive7218 (25.0%)0.506
 Negative7723 (29.9%)
Histological grade
 High408 (20.0%)0.274
 Medium9330 (32.3%)
 Low153 (20.0%)
TNM stage
 I144 (28.6%)0.234
 II5715 (26.3%)
 III4420 (45.5%)
 IV31 (33.3%)
Tumor size
 <5 cm8927 (30.3%)0.348
 ≥5 cm6014 (23.3%)
Tumor Site
 Upper thorax173 (17.6%)0.364
 Middle thorax11130 (27.0%)
 Lower thorax218 (38.1%)
Early-stage versus advanced-stage
 Early-stage185 (27.8%)0.979
 Advanced-stage13136 (27.5%)

Statistical significance was determined by means of Chi-squared test.