CD146 Promoter Polymorphism (rs3923594) Is Associated with Recurrence of Clear Cell Renal Cell Carcinoma in Chinese Population

Table 5

Univariate and multivariate Cox regression analysis in patients with localized ccRCC.

Variables	RFS
	Univariate			Multivariate
	HR	95% CI	value	HR	95% CI	value
Age (≤57 versus >57)	1.290	0.601–3.684	0.372
Sex (male versus female)	1.481	0.714–3.576	0.382
Tumor size (≤2 versus >2 cm)	2.109	1.240–4.843	0.006	1.853	1.008–3.451	0.023
Stage (T1 + T2 versus T3 + T4)	4.828	2.754–8.266	<0.001	2.963	1.438–5.157	0.005
Grade (1 + 2 versus 3 + 4)	3.996	2.212–7.249	<0.001	2.852	1.339–5.274	0.003
Presence of necrosis (yes versus no)	2.548	1.339–5.982	0.012	1.985	1.021–3.682	0.019
rs3923594 (GG versus GT + TT)	2.788	1.186–6.586	0.021	2.116	1.053–4.107	0.034