Research Article
Serum Soluble ST2 and Diastolic Dysfunction in Hypertensive Patients
Table 2
Clinical, laboratory, and echocardiographic data of patients in the two groups.
| | Group A (HBP without LVH) | Group B (HBP with LVH) | |
| | Number | 38 | 49 | | | Age | 59.67 ± 14.47 | 65.17 ± 8.501 | .024 | | Men | 10 (26.3%) | 16 (32.6%) | .006 | | Women | 28 (73.7%) | 33 (67.4%) | .014 | | SBP (mmHg) | 151.00 ± 26.91 | 146.63 ± 24.61 | .796 | | DBP (mmHg) | 88.96 ± 11.70 | 95.55 ± 77.61 | .413 | | PP | 60.92 ± 11.73 | 62.04 ± 18.37 | .002 | | MAP | 106.16 ± 13.11 | 119.97 ± 18.61 | .001 | | BMI (kg/m2) | 30.49 ± 5.19 | 30.58 ± 5.43 | .03 | | Uric acid (mg/dL) | 6.57 ± 1.76 | 5.19 ± 2.06 | .079 | | Creatinine (mg/dL) | 0.88 ± 0.49 | 0.85 ± 0.28 | .246 | | Urea (mg/dL) | 31.02 ± 21.91 | 31.07 ± 20.31 | .790 | | Serum albumin (g/dL) | 3.5 ± 0.2 | 3.9 ± 1.2 | .000 | | Serum glucose (mg/dL) | 107.83 ± 23.67 | 107.97 ± 35.40 | .338 | | Total cholesterol (mg/dL) | 187.52 ± 58.84 | 201.79 ± 57.34 | .862 | | HDL cholesterol (mg/dL) | 47.05 ± 8.94 | 48.59 ± 13.46 | .577 | | LDL cholesterol (mg/dL) | 115.34 ± 38.83 | 117.38 ± 42.91 | .522 | | Triglycerides (mg/dL) | 128.73 ± 89.81 | 135.67 ± 68.92 | .070 | | Na (mEq/L) | 138.58 ± 2.81 | 139.32 ± 8.24 | .476 | | K (mEq/L) | 4.28 ± 0.48 | 4.38 ± 0.53 | .850 | | ST2 (ng/mL) | 29.91 ± 24.12 | 36.03 ± 29.91 | .003 | | Ascending aorta (mm) | 26.46 ± 8.97 | 31.46 ± 5.38 | .002 | | Left atrium size (mm) | 31.13 ± 8.98 | 34.81 ± 7.55 | .056 | | Left atrium area (mm) | 5.79 ± 9.55 | 9.74 ± 10.63 | .003 | | Left atrium area index (mm) | 21.32 ± 8.56 | 28.47 ± 7.21 | .001 | | End-systolic interventricular septum (mm) | 9.46 ± 5.37 | 13.92 ± 5.78 | .002 | | End-diastolic interventricular septum (mm) | 9.71 ± 1.53 | 13.01 ± 1.56 | .000 | | End-systolic LV posterior wall (mm) | 10.78 ± 4.77 | 13.88 ± 5.13 | .012 | | End-diastolic LV posterior wall (mm) | 10.01 ± 1.43 | 12.11 ± 2.32 | .000 | | End-systolic LV size (mm) | 24.77 ± 14.07 | 28.30 ± 11.17 | .224 | | End-diastolic LV size (mm) | 42.52 ± 6.11 | 44.57 ± 8.95 | .306 | | Right ventricle size (mm) | 26.35 ± 4.28 | 26.28 ± 9.11 | .074 | | Stroke volume (mL) | 13.92 ± 22.96 | 37.37 ± 34.70 | .001 | | LV mass (g/m2) | 145.4 ± 62.2 | 262.9 ± 83.6 | .000 | | LV mass index | 44.95 ± 85.30 | 164.15 ± 128.93 | .000 | | IVRT (ms) | 127.96 ± 72.47 | 98.38 ± 49.03 | .009 | | EDT (ms) | 211.72 ± 120.06 | 218.64 ± 71.65 | .005 |
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HBP: hypertension; LVH: left ventricular hypertrophy; SBP: systolic blood pressure; DBP: diastolic blood pressure; PP: pulse pressure; MAP: mean arterial pressure; BMI: body mass index; LV: left ventricle; IVRT: isovolumetric relaxation time; EDT: mitral E wave deceleration time.
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