Predictive Role of F₂-Isoprostanes as Biomarkers for Brain Damage after Neonatal Surgery

Figure 5

Receiver operating characteristic (ROC) curve analysis for NPBI at 72 hours after surgery. The area under the curve indicates that NPBI at 72 hours after surgery allows to differentiate neonates with nonparenchymal injury from no injury. The area under the curve was 0.785 (95% confidence interval: 0.595–0.975), with 66.7% specificity and 90.9% sensitivity. 1.34 μM/l or higher was identified as predictive threshold to have nonparenchymal injury.