Research Article

miR-202 Suppresses Cell Proliferation by Targeting FOXR2 in Endometrial Adenocarcinoma

Figure 4

FOXR2 is upregulated in EAC and is associated with poor prognosis. (a) Expression of FOXR2 and p-AKT was downregulated by miR-202 in KLE cells and was upregulated by miR-202 inhibitor in AN3CA cells assayed by Western blotting. β-Actin was used as internal control. (b, c) Positive expression of FOXR2 in EAC is higher compared with that in control tissues. (d) High FOXR2 expression level was significantly associated with poor prognosis. (e) In miR-202-positive EAC tissues, the FOXR2-positive rate is significantly lower than that in miR-202-negative tissues. (f) Data illustrates the FOXR2-positive cases in miR-202-positive and miR-202-negative EAC tissues. , .
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