Overexpression of miR-24 Is Involved in the Formation of Hypocoagulation State after Severe Trauma by Inhibiting the Synthesis of Coagulation Factor X

Table 2

Demographics.

Variable	Healthy controls ()	Non-TIC ()	TIC ()	value
Age (y)	42.27 ± 14.59	47.96 ± 12.68	46.50 ± 15.21	0.43
Male, n (%)	11 (73.33%)	20 (71.43%)	6 (75%)	0.98
Blunt, n (%)	N/A	23 (82.14%)	6 (75%)	0.64
Hours from scene	N/A	8.2 ± 3.1	7.6 ± 4.0	0.80
Injury Severity Score	N/A	25 (16–54)	34 (26–45)	0.03
Shock index	N/A	0.74 (0.53–2.00)	0.98 (0.60–1.52)	0.04
INR	N/A	1.13 (0.93–1.43)	1.70 (1.56–2.11)	<0.01
Transfused, n (%)	N/A	17 (60.71%)	8 (100%)	0.03
Packed red blood cells (U)	N/A	3.5 (0–20)	9 (0–19)	0.13
Fresh frozen plasma (mL)	N/A	0 (0–1150)	425 (0–2000)	0.14
Platelets (U)	N/A	0 (0–3)	1 (1–3)	<0.01
In-hospital mortality, n (%)	N/A	2 (7.14%)	2 (33.33%)	0.21
LOS in the hospital (d)	N/A	19.93 ± 14.02	23.63 ± 15.84	0.53
LOS in the ICU (d)	N/A	0 (0–11)	0 (0–9)	0.61

INR: international normalized ratio; LOS: length of stay; : values in boldface.