Research Article
Associations between Interleukin-31 Gene Polymorphisms and Dilated Cardiomyopathy in a Chinese Population
Table 5
Associations between IL-31 SNPs and patients’ overall survival.
| | Characteristics | Genotype | Overall survival | | Multivariate survival analysisa | Univariate survival analysis | | HR | 95%CI | value | HR | 95%CI | value |
| | Model | | | | | | | | | rs4758680 | | | | | | | | | Dominant | CC | 1 | — | — | 1 | — | — | | CA/AA | 0.548 | 0.345–0.869 | 0.011 | 0.530 | 0.337–0.834 | 0.006 | | Recessive | CC/CA | 1 | — | — | 1 | — | — | | AA | 0.868 | 0.399–1.888 | 0.722 | 0.778 | 0.361–1.678 | 0.522 | | Overdominant | CC/AA | 1 | — | — | 1 | — | — | | CA | 0.503 | 0.297–0.852 | 0.011 | 0.516 | 0.310–0.861 | 0.011 | | rs7977932 | | | | | | | | | Dominant | CC | 1 | — | — | 1 | — | — | | CG/GG | 1.161 | 0.666–2.024 | 0.599 | 1.275 | 0.736–2.211 | 0.386 | | Recessive | CC/CG | 1 | — | — | 1 | — | — | | GG | 3.739 | 0.862–16.218 | 0.078 | 3.482 | 0.841–14.414 | 0.085 | | Overdominant | CC/GG | 1 | — | — | 1 | — | — | | CG | 1.096 | 0.619–1.943 | 0.753 | 1.211 | 0.687–2.133 | 0.508 |
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aMultivariate survival analysis adjusted for age, gender, LVEDD, and LVEF.
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