Association of GCLM -588C/T and GCLC -129T/C Promoter Polymorphisms of Genes Coding the Subunits of Glutamate Cysteine Ligase with Ischemic Heart Disease Development in Kazakhstan Population
Table 1
Comparison of IHD patient group and control subjects.
Characteristics
IHD group
Control group
tst
value
n
360
341
Age (y)
1923–1970 (60 ± 12.04)
1921–1970 (52 ± 13.23)
0.51
0.699
Gender, n (%)
Male
91 (25.27)
109 (31.96)
1.628
0.350
Female
269(74.72)
232 (68.03)
1.042
0.486
Ethnicity, n (%)
Kazakhs
230 (63.88)
237 (69.5)
0.908
0.530
Other Asians
28 (8.21)
33 (9.68)
0.840
0.555
Russians
102 (28.32)
71 (20.82)
1.925
0.305
Smoking status, n (%)
Smokers
41(11.39)
57 (16.71)
1.796
0.323
Nonsmokers
319 (88.61)
284 (83.28)
0.758
0.587
Total cholesterol (mmol/l)
>5.02 (5.47 ± 0.09)
<5.02 (4.01 ± 0.06)
13.498
0.047
Blood pressure (mmHg)
>140/90
120/60
—
—
There were no statistically significant differences in age, gender, and smoking status between the control and experimental groups ( for all characteristics).
