Association of GCLM -588C/T and GCLC -129T/C Promoter Polymorphisms of Genes Coding the Subunits of Glutamate Cysteine Ligase with Ischemic Heart Disease Development in Kazakhstan Population

Table 4

Allele frequencies of GCLM (-588C/T) and GCLC (-129T/C) promoter polymorphism genes in Kazakhstan population (controls) and other earlier studied Asian and European populations.

Polymorphism	Alleles	Frequency of alleles
		Control cohort (Kazakhstan population)	Data from different sources
			Asian populations	European populations
GCLM (-588C/T)	C	0.861	0.836–0.906 [36]	0.80–0.847, [28]
	T	0.139	0.094–0.164 [36]	0.160–0.20 [28, 36]
GCLC (-129T/C)	C	0.889	0.911 [11]	0.929–0.931 [27, 37],
	T	0.111	0.089 [11]	0.069–0.071 [27, 37]