Predictive Value of MiR-219-1, MiR-938, MiR-34b/c, and MiR-218 Polymorphisms for Gastric Cancer Susceptibility and Prognosis

Table 1

Characteristics, genotype distributions, and allele frequencies of SNPs between GC and controls.

Characteristics	Gastric cancer ()	Controls ()
Age	61.04 ± 11.34	59.15 ± 10.04	<0.001
Gender
Male	648 (72.2%)	714 (72.0%)	0.898
Female	249 (27.8%)	278 (28.0%)
H. pylori infection
Yes	603 (67.6%)	487 (49.1%)	<0.001
No	289 (32.4%)	505 (50.9%)
Rs213210
T/T	266 (30.0%)	241 (24.4%)	0.020
C/T	422 (47.6%)	519 (52.5%)
C/C	199 (22.4%)	229 (23.1%)
T	954 (53.8%)	1001 (50.6%)	0.052
C	820 (46.2%)	977 (47.9%)
Rs2505901
T/T	587 (65.5%)	635 (64.3%)	0.853
C/T	274 (30.6%)	313 (31.7%)
C/C	35 (3.9%)	40 (4.0%)
T	1448 (80.8%)	1583 (80.1%)	0.593
C	344 (19.9%)	393 (19.9%)
Rs4938723
T/T	405 (45.4%)	476 (48.1%)	0.287
C/T	396 (44.3%)	430 (43.4%)
C/C	92 (10.3%)	84 (8.5%)
T	1206 (67.5%)	1382 (69.8%)	0.133
C	580 (32.5%)	598 (30.2%)
Rs11134527
A/A	345 (38.6%)	394 (39.8%)	0.737
A/G	412 (46.1%)	439 (44.3%)
G/G	137 (15.3%)	158 (15.9%)
A	1102 (61.6%)	1227 (61.9%)	0.867
G	686 (38.4%)	755 (38.2%)

Data were described as mean ± SD or (%).