Research Article
Predictive Value of MiR-219-1, MiR-938, MiR-34b/c, and MiR-218 Polymorphisms for Gastric Cancer Susceptibility and Prognosis
Table 2
Genotype distribution comparisons and odds ratio (OR) estimates of 4 SNPs for GC.
| | Genotype | Case | Control | OR (95% CI | |
| | Rs213210 | | | | | | T/T | 266 (30.0%) | 241 (24.4%) | 1.00 | 0.026 | | C/T | 422 (47.6%) | 519 (52.5%) | 0.74 (0.60–0.92) | | | C/C | 199 (22.4%) | 229 (23.1%) | 0.80 (0.62–1.04) | | | C/T-C/C | 621 (70.0%) | 748 (75.6%) | 0.76 (0.62–0.93) | 0.009 | | Rs2505901 | | | | | | T/T | 587 (65.5%) | 635 (64.3%) | 1.00 | 0.870 | | C/T | 274 (30.6%) | 313 (31.7%) | 0.95 (0.78–1.16) | | | C/C | 35 (3.9%) | 40 (4.0%) | 0.93 (0.58–1.49) | | | C/T-C/C | 309 (34.5%) | 353 (35.7%) | 0.95 (0.79–1.15) | 0.600 | | Rs4938723 | | | | | | T/T | 405 (45.4%) | 476 (48.1%) | 1.00 | 0.230 | | C/T | 396 (44.3%) | 430 (43.4%) | 1.09 (0.90–1.32) | | | C/C | 92 (10.3%) | 84 (8.5%) | 1.32 (0.95–1.82) | | | C/T-C/C | 488 (54.6%) | 514 (51.9%) | 1.13 (0.94–1.35) | 0.200 | | Rs11134527 | | | | | | A/A | 345 (38.6%) | 394 (39.8%) | 1.00 | 0.700 | | A/G | 412 (46.1%) | 439 (44.3%) | 1.07 (0.88–1.31) | | | G/G | 137 (15.3%) | 158 (15.9%) | 0.97 (0.74–1.28) | | | A/G-G/G | 549 (61.4%) | 597 (60.2%) | 1.05 (0.87–1.26) | 0.063 |
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ORs and P values were adjusted by age, gender, and H. pylori infection using logistic regression model. Here, a means adjusted value.
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