Research Article

Expression of AdipoR1 and AdipoR2 Receptors as Leptin-Breast Cancer Regulation Mechanisms

Table 1

Relative expression of AdipoR1 and AdipoR2.

Cell lineLeptin concentration (ng/mL)2−ΔΔCT AdipoR12−ΔΔCT AdipoR2

MCF-7102.754 ± 0.70133.31 ± 16.006
1001.63 ± 1.7422.354 ± 14.006
10001.615 ± 1.20927.607 ± 21.102
HCC1937100.162 ± 0.1291.01 ± 0.755
1001.019 ± 1.4230.664 ± 0.502
10000.27 ± 0.270.986 ± 0.597

2−ΔΔCT Relative expression using BACT as a constitutive gene. The data is expressed as mean ± SD, . In statistical Mann–Whitney U test, significance with regard to the control , .