LncRNA NEAT1 Regulates Cell Viability and Invasion in Esophageal Squamous Cell Carcinoma through the miR-129/CTBP2 Axis

Figure 5

CTBP2 restoration overturned NEAT1 knockdown- or miR-129 overexpression-induced suppressive role on viability and invasion of ESCC cells. (a, b) EC109 cells were transfected with si-NEAT1, si-control, si-NEAT1 + pcDNA, or si-NEAT1 + pcDNA-CTBP2; then, CCK-8 and transwell invasion assays were performed to determine cell viability and invasiveness. (c, d) EC109 cells were transfected with miR-129, miR-control, miR-129 + pcDNA, or miR-129 + pcDNA-CTBP2; then, CCK-8 and transwell invasion assays were conducted to measure cell viability and invasiveness. .

(a)

(b)

(c)

(d)