Disease Markers / 2017 / Article / Tab 2

Research Article

Longitudinal Assessment of Transorbital Sonography, Visual Acuity, and Biomarkers for Inflammation and Axonal Injury in Optic Neuritis

Table 2

Sonographic features and visual outcomes of patients and OPN and NfH values assessed at baseline (T0) and after 1 year (T12) of follow-up.

ParameterTON patients affected eye ()Healthy controls () value

ONSD, mmT06.3 (6.0–6.5)5.2 (4.8–5.5)<0.001
T125.3 (4.9–5.6)
value<0.001
OND, mmT03.4 (2.9–3.8)2.7 (2.5–2.9)<0.001
T122.8 (2.7–3.0)
value0.001
Visual acuityT00.80 (0.40–1.00)
T121.00 (0.90–1.00)
value<0.001

T: time; ON: optic neuritis; ONSD: optic nerve sheath diameter, mm; OND: optic nerve diameter, mm; mm: millimeter; OPN: osteopontin; NfH: neurofilament heavy chain; ng/ml: nanogramm/milliliter; n: number of patients. Data are reported as median (IQR).

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