Serum HMGB1 as a Potential Biomarker for Patients with Asbestos-Related Diseases

Table 1

Basic characteristics of the subjects.

	Control; ()	AE < 10 Y; ()	AE ≥ 10 Y; ()	PP; (1)	Asbestosis; (1)	MPM; ()
Age, y; median (IQR)	67 (8)	66 (8)	67 (7)	68 (10)	73 (16)^#	66 (15)^●
Gender
Male, n (%)	44 (62.0)	47	21 (16.3)	33 (40.7)	8	7 (46.7)
Female, n (%)	27 (38.0)	123 (72.4)	108 (83.7)	48 (59.3)	23 (74.2)	8 (53.3)
Smoker, n (%)	10 (14.5)	16 (9.9)	7 (5.6)	13 (17.1)	1 (3.3)	4 (26.7)
Drinker, n (%)	5 (7.3)	9 (5.6)	5 (4.0)	6 (7.9)	0 (0.0)	4 (26.7)
Potential exposure level, mg/m^3-years (median (IQR))	NA	17.7 (31.9)	70.8 (83.9)^#	50.2 (77.0) ^#▲	11.9 (83.3)^#▲	11.0 (13.1)^#
Exposure duration, y (median (IQR))	NA	5 (3.0)	14 (5.0)^#	10 (8.5) ^#▲	10 (10.0)^#▲	14 (12.5)^▲

PP: pleural plague; AE: asbestos-exposed; MPM: malignant pleural mesothelioma; IQR: interquartile range; NA: not applicable; Y: years.
versus control group, ; # versus AE < 10 Y group, ; ▲ versus AE ≥ 10 Y group, ; ● versus asbestosis group, .