Serum HMGB1 as a Potential Biomarker for Patients with Asbestos-Related Diseases

Table 2

Factors influencing serum levels of HMGB1 in univariable and multiple linear regression.

Predictor	Univariable analysis			Multivariable analysis^#
		SE	value		SE	value
Age		0.002	0.66
Gender (female/male)		0.03	0.07
Smoking (nonsmoker/smoker)		0.04	0.08
Drinking (nondrinker/drinker)		0.05	0.35
PP group versus control group	0.20	0.04	0.0001	0.20	0.04	<0.0001
AE < 10 y group versus control group	0.23	0.04	<0.0001	0.23	0.04	<0.0001
AE ≥ 10 y group versus control group	0.22	0.04	<0.0001	0.22	0.04	<0.0001
Asbestosis group versus control group	0.44	0.06	<0.0001	0.44	0.06	<0.0001
MPM group versus control group	0.48	0.07	<0.0001	0.48	0.07	<0.0001

dependent variable was natural logarithm form; ^#estimated with forward stepwise method; : regression coefficient; SE: standard error.