Research Article
Differential Expression of Glycolysis-Related Proteins in Follicular Neoplasms versus Hürthle Cell Neoplasms: A Retrospective Analysis
Table 7
Cox-proportional hazard analysis for overall survival in follicular carcinomas and Hürthle cell carcinomas.
| Parameter | Univariate analysis | Multivariate analysis | Odd ratio | 95% CI | value | Odd ratio | 95% CI | value |
| Age ≥ 45 (years) | 0.017 | 0.001–23.502 | 0.270 | | | | Female sex | 0.326 | 0.053–1.994 | 0.225 | | | | Tumor size >2.0 (cm) | 2.151 | 0.240–19.242 | 0.493 | | | | Capsular invasion | 0.546 | 0.060–4.899 | 0.589 | | | | Vascular invasion | 2.530 | 0.421–15.201 | 0.310 | | | | Extrathyroidal extension | 3.903 | 0.651–23.401 | 0.136 | | | | Lymph node metastasis | 15.742 | 1.723–143.770 | 0.014 | 15.742 | 1.723–143.770 | 0.014 | GLUT-1 positivity | n/a | n/a | n/a | | | | Hexokinase II positivity | n/a | n/a | n/a | | | | CAIX positivity | n/a | n/a | n/a | | | | MCT4 (T) positivity | 0.790 | 0.087–7.225 | 0.838 | | | | Glycolysis type | n/a | n/a | n/a | | | |
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n/a: not applicable. Glycolysis type was defined as those positive for two or more of the glycolysis related proteins.
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