Usefulness of Age-Stratified N-Terminal Prohormone of Brain Natriuretic Peptide for Diagnosing Kawasaki Disease
Table 1
Demographic characteristics and laboratory findings at diagnosis in patients with complete Kawasaki disease (KD), incomplete KD, and simple febrile illness (control).
Complete KD
Incomplete KD
Control
n
Value
n
Value
n
Value
Age (years)
214
2.8 ± 1.8
129
2.3 ± 2.0
62
2.9 ± 2.7
Sex (boy/girl)
214
136/78
129
75/54
62
47/15
Total fever duration (days)
214
6.0 ± 1.8
129
6.3 ± 2.5
62
5.3 ± 4.5
Duration of fever until IVIg (days)
214
4.2 ± 1.9
129
4.5 ± 2.5
62
4.8 ± 3.9
White blood cell (count/mm3)
214
14,561 ± 4855
129
13,955 ± 5557
62
12,268 ± 4753†
Neutrophil (%)
213
66.3 ± 15.7
129
56.8 ± 17.3†
62
56.0 ± 21.0†
Hemoglobin (g/dL)
214
11.4 ± 1.1
129
11.2 ± 1.2
62
11.5 ± 1.3
Platelet (×103/mm3)
214
343 ± 104
129
370 ± 145
62
279 ± 97†,‡
Erythrocyte sedimentation rate (mm/h)
89
64.3 ± 26.6
50
69.3 ± 32.8
21
34.7 ± 32.0†,‡
C-reactive protein (mg/dL)
214
8.1 ± 5.3
129
7.0 ± 5.6
62
4.8 ± 5.0†,¶
Aspartate aminotransferase (U/L)
212
92 ± 138
128
66 ± 104
62
85 ± 132
Alanine aminotransferase (U/L)
212
111.3 ± 170.8
128
67.8 ± 112.9
62
63.4 ± 131.8
Total bilirubin (mg/dL)
139
1.1 ± 1.4
82
0.7 ± 0.8
28
0.6 ± 0.4
Total protein (g/dL)
198
6.4 ± 0.8
117
6.5 ± 0.7
61
6.5 ± 0.6
Albumin (g/dL)
214
3.6 ± 0.6
129
3.7 ± 0.5
62
3.9 ± 0.4†,¶
Lactate dehydrogenase (U/L)
81
623 ± 160
53
638 ± 276
24
745 ± 258
Creatine kinase (IU/L)
181
151 ± 376
114
120 ± 248
60
272 ± 503¶
Creatine kinase-MB (ng/mL)
206
7.3 ± 10.5
122
4.8 ± 8.3
57
12.2 ± 11.9†,‡
Myoglobin (ng/mL)
130
25.4 ± 60.2
85
19.0 ± 18.6
26
74.0 ± 92.4†,‡
Troponin I (ng/mL)
197
0.02 ± 0.04
115
0.01 ± 0.01
45
0.01 ± 0.01
N-terminal prohormone of brain natriuretic peptide (pg/mL)
214
1785 ± 2858
129
1153 ± 1725
62
311 ± 400†,¶
IVIg: intravenous immunoglobulin; KD: Kawasaki disease. Data are shown as mean ± SD. .† versus complete KD. ¶.‡ versus incomplete KD.
