Research Article
Usefulness of Age-Stratified N-Terminal Prohormone of Brain Natriuretic Peptide for Diagnosing Kawasaki Disease
Table 2
Laboratory findings at diagnosis in patients with complete and incomplete Kawasaki disease (KD) and simple febrile illness (control) by age.
| | Complete KD | Incomplete KD | Control | | n | Value | n | Value | n | Value |
| | <6 months | | | | | | | | n (%) | 21 | 21 (9.8) | 25 | 25 (19.4) | 8 | 8 (12.9) | | Age (years) | 21 | 0.4 ± 0.1 | 25 | 0.3 ± 0.1 | 8 | 0.3 ± 0.2 | | White blood cell (count/mm3) | 21 | 13,776 ± 4361 | 25 | 16,460 ± 6412 | 8 | 13,338 ± 6342 | | Erythrocyte sedimentation rate (mm/h) | 13 | 42.7 ± 21.8 | 7 | 65.6 ± 17.6 | 3 | 37.3 ± 20.5 | | C-reactive protein (mg/dL) | 21 | 8.1 ± 5.9 | 25 | 8.7 ± 4.7 | 8 | 3.3 ± 2.7‡ | | N-terminal prohormone of brain natriuretic peptide (pg/mL) | 21 | 3404 ± 3844 | 25 | 1846 ± 1811 | 8 | 669 ± 660 | | 6–12 months | | | | | | | | n (%) | 20 | 20 (9.3) | 22 | 22 (17.1) | 11 | 11 (17.7) | | Age (years) | 20 | 0.8 ± 0.2 | 22 | 0.7 ± 0.1 | 11 | 0.8 ± 0.2 | | White blood cell (count/mm3) | 20 | 16,360 ± 3960 | 22 | 13,250 ± 6981 | 11 | 10,982 ± 3631 | | Erythrocyte sedimentation rate (mm/h) | 10 | 75.3 ± 28.6 | 7 | 54.0 ± 34.9 | 2 | 2.0 ± 0.0 | | C-reactive protein (mg/dL) | 20 | 7.1 ± 4.6 | 22 | 4.7 ± 5.2 | 11 | 3.7 ± 4.6 | | N-terminal prohormone of brain natriuretic peptide (pg/mL) | 20 | 2241 ± 3322 | 22 | 882 ± 1381 | 11 | 301 ± 310† | | 12–24 months | | | | | | | | n (%) | 39 | 39 (18.2) | 21 | 21 (16.3) | 12 | 12 (19.4) | | Age (years) | 39 | 1.6 ± 0.3 | 21 | 1.5 ± 0.3 | 12 | 1.6 ± 0.3 | | White blood cell (count/mm3) | 39 | 14,341 ± 4611 | 21 | 12,886 ± 4688 | 12 | 12,967 ± 3444 | | Erythrocyte sedimentation rate (mm/h) | 17 | 64.5 ± 23.8 | 7 | 59.6 ± 30.5 | 4 | 39.8 ± 38.2 | | C-reactive protein (mg/dL) | 39 | 6.4 ± 4.2 | 21 | 4.6 ± 4.4 | 12 | 4.5 ± 4.2 | | N-terminal prohormone of brain natriuretic peptide (pg/mL) | 39 | 1372 ± 1387 | 21 | 1297 ± 1951 | 12 | 398 ± 560†,¶ | | >24 months | | | | | | | | n (%) | 134 | 134 (62.6) | 61 | 61 (47.3) | 31 | 31 (50.0) | | Age (years) | 134 | 3.8 ± 1.5 | 61 | 4.0 ± 1.6 | 31 | 4.9 ± 2.5 | | White blood cell (count/mm3) | 134 | 14,479 ± 5096 | 61 | 13,551 ± 4657 | 31 | 12,177 ± 5166 | | Erythrocyte sedimentation rate (mm/h) | 49 | 67.8 ± 26.0 | 29 | 76.2 ± 34.9 | 12 | 37.8 ± 34.2,‡ | | C-reactive protein (mg/dL) | 134 | 8.8 ± 5.5 | 61 | 7.9 ± 6.0 | 31 | 5.8 ± 5.8† | | N-terminal prohormone of brain natriuretic peptide (pg/mL) | 134 | 1583 ± 2863 | 61 | 916 ± 1675† | 31 | 188 ± 154†,¶ |
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KD: Kawasaki disease. Data are shown as mean ± SD. . † versus complete KD. ¶. ‡ versus incomplete KD.
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