Research Article

Are Fusion Transcripts in Relapsed/Metastatic Head and Neck Cancer Patients Predictive of Response to Anti-EGFR Therapies?

Table 2

Summary of the gene fusions detected in patients treated with cetuximab and chemotherapy and selected for the extremities of response (see [10]).

Patients harboring gene fusionsN (%) value§
Long PFS (14)Short PFS (26)

Absence4/1412/260.3295§
Presence10/1414/26
1 for each patient5/1010/140.4028§
>1 for each patient5/104/14
Only mRNA in the fusion6/1013/140.1222§
LncRNA in the fusion8/102/140.0027§
CD274/PDCD1LG2 fusion0/107/140.0188§

§The values are reported as the two-sided Fisher exact test.