Increased Risk of the APOB rs11279109 Polymorphism for CHD among the Kuwaiti Population
Table 3
Association of the risk factors with the APOB signal peptide polymorphism in the Kuwaiti population investigated in this study ().
Variable
Genotypes
value
APOB signal peptide polymorphism
II
ID
DD
n (%)
n (%)
n (%)
Sex
0.692
Male
264 (55.7)
151 (31.9)
59 (12.4)
Female
150 (57.5)
84 (32.2)
27 (10.3)
BMI (kg/m2)
0.511
<25
77 (53.8)
44 (30.8)
22 (15.4)
25–<30
145 (54.9)
88 (33.3)
31 (11.7)
≥30
190 (59.2)
98 (30.5)
33 (10.3)
Ethnicity
0.015
Arab
192 (58.4)
102 (31.0)
35 (10.6)
Bedouin Arab
51 (45.1)
38 (33.6)
24 (21.2)
HU
71 (61.2)
38 (32.8)
7 (6.0)
Iranian
98 (56.3)
56 (32.2)
20 (11.5)
Medical history of T2DM
0.803
No
269 (56.5)
154 (32.4)
53 (11.1)
Yes
145 (56.0)
81 (31.3)
33 (12.7)
Medical history of hypertension
0.986
No
211 (56.6)
119 (31.9)
43 (11.5)
Yes
203 (56.1)
116 (32.0)
43 (11.9)
Medical history of high cholesterol
0.616
No
264 (57.3)
147 (31.9)
50 (10.8)
Yes
150 (54.7)
88 (32.1)
36 (13.2)
Medical history of high triglycerides
0.637
No
358 (55.7)
209 (32.5)
76 (11.8)
Yes
56 (60.9)
26 (28.2)
10 (10.9)
Family history of cardiac diseases
0.814
No
316 (55.8)
182 (32.2)
68 (12.0)
Yes
98 (58.0)
53 (31.3)
18 (10.7)
values are generated by chi-square test. T2DM: type 2 diabetes mellitus; HU: heterogeneous population whose mothers are not Arabs, or whose ancestry is unidentified.
