Increased Risk of the APOB rs11279109 Polymorphism for CHD among the Kuwaiti Population

Table 4

Significant independent risk factors associated with CHD selected by the multivariate logistic regression analysis (CHD patients = 372 and controls = 363).

Variables	Odds ratio (adjusted)	^a95% CI
APOB signal peptide polymorphism
II (reference group)	1.00
ID	1.14	0.77–1.70
DD	2.43	1.34–4.41
Smoking status	6.69	3.93–11.39
Ever smoked
Medical history of diabetes mellitus	5.73	3.77–8.71
Yes
Medical history of high cholesterol	1.85	1.24–2.76
Yes
Family history of cardiac diseases	1.69	1.08–2.63
Yes

^a95% CI = 95% confidence interval for odds ratio. indicated significance of <0.001. Included variables were sex, age, ethnicity, BMI, smoking status, medical history of diabetes mellitus, hypertension, high cholesterol, high TGs, family history of cardiac diseases, and signal peptide polymorphism.