Research Article

Increased Risk of the APOB rs11279109 Polymorphism for CHD among the Kuwaiti Population

Table 5

Statistical comparison of APOB rs11279109 genotype distribution () in different genetic models between Kuwaiti CHD patients and controls after controlling for age, sex, BMI, ethnicity, smoking status, and medical history of hypercholesterolemia.

ModelControls
()
CHD patients
()
OR (95% CI)

Codominant
 II204 (61.4%)174 (51.8%)1
 ID104 (31.3%)108 (32.1%)1.24 (0.88–1.76)
 DD24 (7.2%)54 (16.1%)2.69 (1.57–4.61)
Dominant
 II204 (61.4%)174 (51.8%)1
 ID + DD128 (38.6%)162 (48.2%)1.51(1.1-2.08)
Recessive
 II + ID308 (92.8%)282 (83.9%)1
 DD24 (7.2%)54 (16.1%)2.49 (1.48–4.2)
Additive332 (30.4%)336 (68.8%)1.5 (1.19–1.89)

CHD: coronary heart disease; OR: odds ratio; CI: confidence interval. value for all models was less than 0.01.