Influence of IL-18 and IL-10 Polymorphisms on Tacrolimus Elimination in Chinese Lung Transplant Patients

Table 1

Allele frequency of CYP3A5, IL-18, and IL-10 polymorphisms in lung transplant recipients ().

Gene	SNP	Genotype			Allele
CYP3A5	rs776746	GG	AG	AA	G	A
		0.471 (24)	0.451 (23)	0.078 (4)	0.696 (71)	0.304 (31)
IL-18	rs5744247	GG	GC	CC	G	C
		0.118 (6)	0.510 (26)	0.373 (19)	0.373 (38)	0.627 (64)
IL-18	rs1946518	CC	CA	AA	C	A
		0.255 (13)	0.451 (23)	0.294 (15)	0.480 (49)	0.520 (53)
IL-10	rs1800896	AA	AG	GG	A	G
		0.863 (44)	0.137 (7)	0 (0)	0.931 (95)	0.069 (7)
IL-10	rs1800872	AA	AC	CC	A	C
		0.412 (21)	0.510 (26)	0.078 (4)	0.667 (68)	0.333 (34)
IL-10	rs3021097	TT	TC	CC	T	C
		0.431 (22)	0.490 (25)	0.078 (4)	0.676 (69)	0.324 (33)