Review Article

Association between IL-4 and IL-4R Polymorphisms and Periodontitis: A Meta-Analysis

Table 4

Meta-analysis of the association between the IL-4 -1099T/G polymorphism and periodontitis.

Genetic model and subgroup Number of studiesHeterogeneityPooled results
(%)OR95% CI for OR

G versus T      
 Overall20.4801.2(0.53–2.71)0.66
GG versus TT      
 Overall2<0.0186.76.58(0.03–11.46)0.73
TG versus TT      
 Overall20.0965.70.57(0.32–1.04)0.07
(GG + TG) versus TT      
 Overall2<0.0193.70.73(0.23–2.34)0.60
GG versus (TT+TG)      
 Overall2<0.0185.90.63(0.03–11.35)0.75